Resources cost far too much compared to just buying the item. A healing potion costs about 120 or so, while in order to make a healing potion from reagents, you need to spend 300 gold on reagents, AND it leaves you with a chance of failure.
Very fun yet difficult, especially the prospect of getting 200% bullet damage. For those who have trouble, take note of the small white pixel in the centre of your ship. As long as the bullets don't his that pixel you'll be okay.
Regarding lasers, listen to the beat, as they activate according to it. Don't be afraid to slow down time using X. The sound may be terrible to listen at, but it'll help you find openings you wouldn't notice otherwise.
Lastly, the final boss was rather... so so. It starts of incredibly boring, making you waste a lot of time before things get interesting, and even then it all depends upon what he changes into.