On level 10, if you kill a skeleton in front of the altar, all the skeletons it spawns die immediately. So you can just hang around and rack up as many kills as you want by walking in circles or whatnot. Kind of amusing!
I'm not colorblind, so I don't know how easy-to-distinguish the colors are for someone who is, but just realized this game would be impossible if you couldn't tell the difference between the different types. Maybe you could add a "colorblind mode" / "shapes mode" which added shape variation to the different types of circles, especially if you're going to sell a mobile version :-)
Adobe changed how they handled save data with Flash Player 10.3. It'll get deleted when you clear your cookies or history, if you use private browsing, etc., even if you do so in a *different* browser (since it's still stored separately, just deleted at the same time). Rate my game down if you like, but there's nothing I can do about it if you set your computer to delete save data.
Nice memory game. I liked most of the patterns, especially toward the end--the paths you chose didn't feel very random. They felt ordered, which helps the player make sense of them and commit them to memory. When things got too tough to simply repeat, you used cues the player can make mental notes of, like symmetry, similarity, or touching each tile once. In the second half of the game, most of the patterns are naturally divided into smaller mental lists. Good job on making an interesting memory game that doesn't feel like work to play. The boss level was a nice touch, too.
I think when a new "blob of mystery matter" appears, it should fade in and not hurt you until 1.0 alpha, so that you can avoid it if it appears on top of you (that's killed me twice, now). Likewise, the grey asteroids should appear at a minimum distance from the ship. "R" key to replay wouldn't work because the ship follows mouse, but a single button to replay would be better than click-move-click. API for high scores since it's a skill game (my best is 115 on normal mode). The alien is great--easy mode isn't as fun since it's missing. You could have an easy mode with the alien, but let the player take a few hits from the alien/asteroid. (Just give the player a little invulnerability timeout so it doesn't hit them on every frame.) Anyway, nice game--addicting and challenging!