When you are level 1-5, take points in the mastery where the gem slowly recedes back to the cave. This is the best use of your points since you won't get far spending them elsewhere in the early levels, where the lack of masteries will make passing tough.
Overall, melee weapons are best. Guns have too little ammo, and are much more varied than melee weapons. Upgrade strength. Bladed is better in the long run, but blunt is good for the beginning when it's too early to find the katana or axe.
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