In light of your response Spicyhorse I am a mouse only user and I find it just as easy if not easier to replicate a shot with a mouse unless you have your mouse sensitivity up whereas you can have minor lag spike with keyboard controls and your power will mess up.
Why does mouse only controls have a repeat fire button and keyboard & mouse controls not have one, this could give some players an advantage. There are two possible solutions, remove the repeat fire button from mouse only controls or add it to keyboard & mouse.
Because it's harder to get the same angle when using mouse only which you can do easily with mouse and keyboard. Swings and roundabouts really. It has better bits, it has worse bits. But since it's been implemented, we've had no real complaints or comments about one being better than the other..... yet ;)
 "Crazy Fairies"){kind=icon}
 "Thousand Dollar Soul"){kind=icon}
Then maybe mouse only will become the standard control method of champions ? :)