Camera culling on unpause should've been fixed in yesterday's patch for the properly reported case of it happening. Make sure you're on the latest version by doing a force refresh (see link for info), and if it's still happening, report the issue in detail following the Bug Reports thread www.kongregate.com/forums/9794/topics/725152-bug-reports
I've received a few reports about the culling system permanently hiding items, but can't reproduce it myself, and nobody has been able to provide a video of it happening so I can't analyze it either. If you want to disable culling, you can do so at [Settings > Performance > Camera Culling].
Report bugs properly following the Bug Reports thread on the forums. I can't do anything based on no information whatsoever.