Gamers Beware: If you want to complete Campaign mode don't select a region with very low purchasing power.
Developers: You should change the $100 min to complete mission 22; it's too low for the regions with low purchasing power.
Mission 22 took me over two hours of gameplay. I had a fully maxed out hotel with 100% on all hotel metrics. But even at 100 pricing, the purchasing power of some of my guests was too low, and they left the hotel upset, bringing the total satisfaction down. I found that usually the start of the month has a higher satisfaction rating (after the balance screen). I was lucky enough to start a month with it at 90-something, and it was just enough to hold out for 4 days before it dropped to under 70. Developers should definitely modify this goal to allow for more people finish the campaign -- maybe I wouldn't have been able to at all if my region had an even lower purchasing power.