Taken and condensed from http://caravaneer.wikia.com/wiki/Tips
After working the starting route (Poca Cosa - Caganel - Drushlak) try to get a couple horses with good carts. Save at Caganel and load up on shoes, go to Verdammter Platz. Avoid the large robber hordes and when you arrive shoes should be $80-$110 each so dump your entire stock. If there's any cheap (>$0.60) medicines stock up on it. Then get 20-30L of fuel carrying items (and hope Platz/Giat has fuel), load up on fuel, buy an ATV and head on to Hara. Upon arrival search for cheap medicine (avoid the Fort) and sell it all to Qubba for ~$2 each, then go Fort Goks and proceed to buy as much of their extremely cheap medicine as you can, if you were fast enough at travelling north it should be in the tens of thousands, then sell to Qubba and it will net you enough money to transition into almost any trade route or playstyle.
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