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dis⋅as⋅trous  /dɪˈzæstrəs, -ˈzɑstrəs/ Show Spelled Pronunciation [di-zas-truhs, -zah-struhs]
–adjective 1. causing great distress or injury; ruinous; very unfortunate; calamitous: The rain and cold proved disastrous to his health.
2. Archaic. foreboding disaster.

Origin:
1580–90; < MF desastreux, It disastroso. See disaster, -ous

Related forms:

dis⋅as⋅trous⋅ly, adverb
dis⋅as⋅trous⋅ness, noun