This is a cool concept. But forcing the player to play through all the regular levels over again with the perspective restricted to a small circle is one of the worst ideas I've ever seen.
Started in Madagascar. 90% of the region became infected, but not a single boat entered or left the Madagascar docks, so my disease was trapped on the island. I purchased all the methods of transmission and maxed out moisture and heat resistance. Nothing could get my disease off Madagascar. This game is so bad. Why is it so highly rated? Stay away from this game.
Once you get to hard, whether or not it's possible to get the achievements in any given run is entirely determined by dumb luck regarding where the guards walk, where they look, where the target walks, and where the game decides to put the exit after you kill the target.
Once you get to professional, there are so many guards on each level that whether or not a path opens up for you to make it to the target and back is based entirely on luck.
Also the guards seem to have spidey sense on every difficulty.
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