Suggestion: Tanks need to react faster (make them more intelligent). It is almost not even worth the 20 TPs for one as it is too stupid to be effective.
If you are using nades, just keep that guy in front of everyone else (I don't have time to go into a long discussion about formation but maybe sometime I'll post in Urbz's forum about this). And close combat? Kirkiss is right. Just move your guy out of the way before CB initiates. Quick tip 1: Mortars are amazing. Quick tip 2: Give anyone with a rifle skill of >27 a BAR at the beginning of the game.
Those having problems with epic bosses, RECONFIGURE your skills. Max out anything manna related. Don't bother with bombs till final level. Go either pure or dual gems (I only used Pure)