Last level is a little too easy - you can just buy 10 lysosomes, recycle your mitochondria and chloroplasts, and use the huge resource boost to spam 100% toxin. Sure, you'll face a bajillion viruses with no defenses, but you'll win before they can actually do any damage. Got an A+ defense rating.
The reduction in stats required for ranks was a good idea. In means more achievable goals, which means more people, plus you get the added tactics of new weapons sooner.
I can't believe some people are asking for a cancel attack. If you could do that you could aim an attack, se ethat it's off, cancel, re-aim and pwn everything. The current system is relatively balanced (being on top IS a disadvantage, and therefore I think Dome Shield should affect the bottom of the station), but whatever else it is it IS very fun. One solution to the "on top is bad" thing is whenever you're in 4 player, call 2v2, left v right. Usually it'll happen, and that's especially fun.
Simple, yet very fun. The impossible badge could get a bit frustrating, but then, they're supposed to be. Generally the game was very good; the simplistic controls made sure the game didn't get too complicated, but there was still plenty of tactics you could work out.