Why isn't there an option when debating Euthyphro of Athens to question the existence of the gods? That's honestly a clear, easy one shot to ruin his theory.
The first pattern for the Glyph lock seems to be bugged. Tried several times, checked the walkthrough, tried the same procedure there several times - still doesn't work. Sad, the game was really good up to this point.
Controls make it seem like the character has butter-covered shoes at all times. Artificial difficulty and the calming, then insulting screen after pressing "Give Up" make this game only enjoyable for masochists. I was gravely disappointed because most of jmtb02's games are amazing, but everyone fails sometimes.
Very much enjoyed the previous installments and the sequels. Therefore, it makes me very disappointed that this game loads to approximately 40% and then stops.
I hope your computer is top of the line. If not, you'll be spending half your time cursing enemies and spikes and the other half for accidentally hitting a crystal or computron. All of the above make it lag for 2-3 seconds each time.
Two other problems: often you can't let got of a a piece without clicking on another, and the link to the site with other games often gets in the way of grabbing a piece. I do like the option to turn the picture off, as that makes it less confusing.