The game seems to be having issues when I load it in a Chrome browser, my default. When I went to Microsoft Edge it worked fine. Despite allowing all cookies and full site permissions this issue persists. (I get a message when I start that cookies couldn't be used and it won't save).
This should be fixed, however you're going to need to clear your save file in Chrome (this is why it works in Edge for you, it didn't have a persisting save). To do this clear your cookies from Kongregate in Chrome's settings.
Seems like your first skill never loaded up, I'll try to find how/why this might happen. There is a chance clearing your cache and reloading will resolve this problem for you. Also if you got a message at the beginning indicating you can't save it could be that. Enabling cookies will solve the problem in that case, but I'll put in a fix for playing with cookies disabled. [Edit: this should be fixed]
Ok, stuck on the first fight, no dialog, no hotkeys, and no buttons to click. I see a grey hand pointing off the bottom of the screen but am unable to do anything with it. Also I can't bring up a menu to mute the music.
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 "Loot Run"){kind=icon}
 "Diggy"){kind=icon}
This should be fixed, however you're going to need to clear your save file in Chrome (this is why it works in Edge for you, it didn't have a persisting save). To do this clear your cookies from Kongregate in Chrome's settings.