Seriously. I did up-right-down-left and got my second ever highest score.
More importantly, I got my highest ever score by NEVER EVER PRESSING UP. I had two rules - 1. If the blocks can go down, they go down. 2. If they must go left or right, the highest number trumps. #2 isn't as set in stone - if I'm running out of room I do the most effective in making space.