Archigeek stated that if you are currently playing a save from before the update, you may not ever spawn the last bosses. You'll need to restart. Once you do however, they all spawn very quickly.
Once you are comfortable with your celle, go straight any any direction and you will quickly come across the bosses. This is the result of an update by Archigeek.
Upon finishing all 10 bosses, you will unlock the ability to build any celle you want with up to 1000 hexes.
Having a hard time? Create a custom with a yellow center and a red on opposite sides. As you evolve create this...
http://img194.imageshack.us/i/noshotse.jpg/
When a red, blue, and yellow touch, the mines shoot missiles. After about 10 seconds of holding space(drop mines), it looks like this...
http://img507.imageshack.us/i/withshots.jpg/
Why does is seem like people that attempt to translate their games into another language are incapable of having it checked by somebody who speaks the intended language well...I'll fix it if you send me the text...
Biggest Complaint: Downward spiral caused by losing a 9x multiplier. The inability to purchase upgrades leads to getting hit more often which leaves you spending all of your earnings (which are low due to the lack of multiplier) on armor repairs. It's difficult to climb out of the hole. Should be more forgiving in this aspect, especially when the cannon isn't powerful enough to destroy the low hanging bombs which traps you between the wall/bomb and an enemy shot. Needs balancing work.
Another note: You don't have to find all of the evil bubbles before beating the boss. You still get credit for finding and killing them when in invincible mode.
If you're having trouble, you've probably missed one of the instructional bubbles. Press P to see the pause menu and check out the map. As you travel away from the starting bubble, the enemies will get stronger. Just do and expanding spiral away from the starter bubble to have the enemies slowly strengthen while you collect all of the bubbles. Makes is very easy. Oh, and change the pause menu to the Q key so that you don't have to reach all of the way over to the P key.
Level 36 (Boss 2: Mothercube) I've found that when it's spinning around you, when you move straight down and north west, you will not be hit by the shots as much. Seems to be the only pattern that I could notice.
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 "BugEat"){kind=icon}
 "Hexcelle"){kind=icon}
 "Wizard Defense"){kind=icon}
 "Hedgehog Launch 2"){kind=icon}
 "Z-Rox"){kind=icon}
 "Space Mutants FROM SPACE!"){kind=icon}
 "Orbitz"){kind=icon}
 "Bubble Tanks 2"){kind=icon}
 "Heavy Weapons"){kind=icon}
 "The irRegularGame of Life"){kind=icon}