First time against the final boss i knocked him out haha the trick is always go for 4 combo first so u get an extra turn on top of chains and then go after defense tiles, then go after counter tiles in that order that way your protected against all attacks and u have a chance to chain others like rage, health, energy.
 "Penguin Overlords"){kind=icon}
 "Axon"){kind=icon}
 "Realm of the Mad God"){kind=icon}
 "Burrito Bison Revenge"){kind=icon}
 "BioGems"){kind=icon}
 "Epic Battle Fantasy"){kind=icon}