This would be a great game if the resolution issue was fixed and help was added to make it clear what was going on. Just add a training level for the first level. I got in the end that it worked like Desktop Tower Defense. But it wasn't clear at all. The resolution setting makes key areas of the game inaccessible, making it unplayable, unless the player clicks show all in the Flash menu.
Based on the feedback, I've added a pause feature (Press P to toggle pause on and off) and support for 4-player offline multiplayer using the keyboard for additional players.