The game would still hold up today if Plague Inc and it's Steam version: Plague Inc. Evolved weren't better in every single way. They don't have the bullsh!t RNG in it. (Also, Madagascar's not your problem there, That's Greenland's role.) If your RNG is so notorious it creates a small meme... That says something about the dev's programming skills back when this game came out 8 years ago. Granted, 2008 was a different time for Flash but still.
I must say, Completing this game 100% (finishing every mode, buying everything possible in each mode, Buying everything in the Bonus Shop, finishing every challenge, getting every medal) is very satisfying for some reason, at least to me. It's not like there's a completion bonus though, so don't get your hopes up. :P