In "you're nuts" difficulty you'll achieve the treasure in way less time than in other settings. And it's not really "you're nuts" difficult, by the way.
i was in virus mode, and i sold all the diseases i had at the moment and bought fever and encephalitys, the visibility droped a good deal, and when i checked the days untill the completion of the vaccine it said "infinite", and the vaccine was never finished. but now i just can't do it again, why?
it was easy, but i guess the difficulty level is not the point, is it?
it's Plato and Descartes disguised as entertainment. And has a happy ending too! Very good, 5 out of 5 for the orginality.