Before prestiging look to see if there are any recipies you can upgrade, even low tier ones. The upgrade will carry accross, the ingredients used will not.
If you can't tell why auto-reincarnation/auto-transcension aren't working, you're either in a challenge, or you've set it to 10^(10^x)) instead of 10^x.
Mythos upgrades 3 and 4 are power up per transcension, once you can instantly transcend hold t or set up the auto-transcension so you instantly transcend.
Research guide (for after reincarnation): shorturl.at/rDNV0
Reincarnation resets challenges.
FAQ:
Why no buy all button: Set to x100 and hold the hotkey.
When should I go up the first time: Pretty much as soon as I can.
How long should I spend whilst grinding runs? Prestige 10 mins, Transcend 30 mins, Prestige 60 mins
I'm stuck at transcends: Get enough transcends to max out your coin production bonus. Then do 30 min runs to get runes to 20/x/30.
Why am I bugged and not getting anything from prestiging: You're autobuying accelerator boosts. Prestige some more.
Why am I so slow after reincarnating? You don't keep challenges over runs.
What researches are good: shorturl.at/rDNV0
Fantastic game. Not got the same "look for forced moves until it's solved" feel as most puzzle games I see, but it also isn't a matter of button mashing, and quit often you can see a thing you want and work back from it.
I regret looking at the comments and finding the main "trick" (core game mechanic) that makes the first seemingly impossible level possible, I think I'd have enjoyed finding that out for myself, but was to interested in finding out about the difficulty curve.
If you stay away from the dragon for a few minutes, it will fall back to sleep (and recover any lost health). You can then continue it's questline. If you defeat it, you can still get a pet adult dragon by raising your own though.
For some reason, got stuck on the road building part of the tutoral, no amount of building roads got me out of it, and the skip button is inaccessable whilst building roads.
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 "Passport Rummy - Card Game"){kind=icon}
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 "10 More Bullets"){kind=icon}
 "Synergism"){kind=icon}
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 "Idle Quest"){kind=icon}
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 "The Chamber"){kind=icon}
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If you stay away from the dragon for a few minutes, it will fall back to sleep (and recover any lost health). You can then continue it's questline. If you defeat it, you can still get a pet adult dragon by raising your own though.