The doors take 10% of your total amount of cash each time you use them, but you skip 2 levels and the one where you respawn is always an easy one. If you want to climb higher, use them. If you want cash, don't. I've reached floor 250 using doors and without them I managed to get the impossible badge (500,000 points scored) at level 110.
Having this in mind its not difficult to get the 63 in-game trophies.
Thank you :)