I don't know if anyone has mentioned this yet, but to all of you whining about getting your guys blown up heres a tip: place a skeleton (or some low level "tower") at the beginning of the castle, and maybe even a few following him. This causes the suiciders to kill them, sparing your more costly towers. If there is a big chain of suiciders then just keep spamming skeletons once one gets blown up (place one where one had just died).
Finally beat the game! I see a lot of comments asking when more shops come out. I'm not exactly sure when they come out, but I unlocked all of them (and there is a lot) just by completing the storyline quests. Upping your reputation with a faction doesn't give you their shop, it raises the damage those certain mercenaries (is that the right word?) do when you use them. Fun game by the way, I enjoyed the 12 hours I "wasted" on it :P
For all of you who haven't noticed, you SHOOT the nuke after you throw it to make it explode. Throw the nuke down and chuck a rock at it or something! :D