Figured i'd point out a few things. Buying truth buildings on my second playthrough, removes most of my wealth and has very little impact on my science. For 2 truth a second, i am giving 500m/s out of 614m/s and only 100k/s science out of 1.5m/s science. As is, i pretty much can't play while i gain truth since it costs a huge amount of wealth. Also wealth gained from discoveries is useless after you start getting 1m/s wealth. Pretty good job so far tho.
Next mole upgrade costs 10.89 Trillion gold, and gives 4b g/s and 33m diamonds/s.
FIRST orbiting laser costs 100 trillion, and gives 4b g/s and 400k diamonds/s.
Your moles are in fact, the best thing to upgrade. Its the doubling their output every upgrade that is making it this way. And since they are the cheapest diamond makers, they have the most x2 modifiers.