The best way to go is to take out the bases that spawn troops. Luckily the towers and crystal housings don't "make the children" like the other houses. So when you get later into the game, just take out the enemies home base with a nice meteor and a nice battalion of troops {: 5/5 for this zerg zerg game.
Love the glitch with the generals and the boss, you run from them but stay close enough to where you hit them (this is with melee only) and they can't hit you. Great.