1)Pick Virus. 2) Start in Canada, New Zealand, Cuba, Greenland, or Madagascar. If you do not get there restart. 3) Sell the starting symptoms, if any, and buy sneezing (unless it is what you started with, just keep it). 4) Buy 1-1-1-0 resistances but no transmissions (they trigger closures). 5) Once four countries are infected, sell sneezing to get rid of visibility. 6) Wait until all countries are infected. If Madagascar closes its shipyards or is not infected in 30 days, restart. 7) Buy all four drug resistances AND sneezing, coughing, and vomiting. 8) After a few days, unlock tiers 2-3, (do not buy tier 4 ever!) keeping whatever symptoms it gives you. 9) Buy fever, fatigue, diarrhea, pulmonary edema, and hypersensitivity. Then save for kidney failure and ataxia.
The game won't hold my achievements, finished the buccaneers quests then quit to do the enforcers guild quests. Reloaded and all the buc quests are gone. Give it 1 star for being so buggy. Fix the bugs and that will go up.