I have a couple of suggestions, and I am including a couple I saw.
Factions of humans.
Volcanoes, deserts, tundra.
Animals.
Wars
More types of houses
Causing big disasters ( earthquakes would make large destroyed areas / big holes, meteors, etc. )
And hopefully just more terrain pieces. Trade would be cool, and if mountains could be mined, that would be cool. Also boats. Big lake = big boats. More types of everything!
I put a bunch of really dangerous stuff on one floor, with the last computer I needed to hack. This one scientist dodged zombies, survived everything I threw at him, and stopped me from hacking the last computer before the end of the game. I lost because of that one guy. That scientist saved the world, and died for it. I was kind of broken up about it.