I highly suggest that you play as a pure.
Higher level equipment requires a good deal of agility. The more you put into stam, the more agility you’ll need from equips, which cost money.
Of course, if this is your first runthrough of the game, you can easily make it to rebirth without needing these equips. Use scrap and dark alien.
When and if you play as a rebirthed character, however, I suggest you play as pure.