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Sorry about spamming the comments, but I just beat epic mode, so I wanted to leave a few tips (some of which are covered by one of the top comments, so give credit to them for parts so the strategy). Definitely get the aerial support, secret weapon, cat tamer, and cat warrior skills (use air strike constantly in the first two sections for the first two skills to appear, the summon no legs a few times for those two skills to appear). Get counter for Matt (and counter x2 when it appears), and definitely get survivor if it shows up (it gives Matt a 30% chance of surviving a strong attack with 1 hp, it saved me a lot against the last two bosses).
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The earlier bosses are doable with strategy; the guardian can deal crazy damage but is effectively neutered by buffing defense and debuffing the boss when Natz's ultimate heal is available, the golem hits hard but isn't bad once you buff defense, and the sand worm is dangerous if it poisons you but is manageable if killed off within a couple of turns after it respawns its tail. Just focus on using Matt's air strike skill frequently (and choose aerial support and secret weapon skills early) and use autolife during boss battles and you should at least reach the zombie hydra without much trouble.
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I was two hits away from finshing off the final boss on epic mode before an eectric spamming satellite dish and a nuke made me almost break my computer (Matt had autolife and full health, but the satellite killed him in one hit and the nuke killed both Matt and Natz). Anyway, epic mode is mainly difficult because the last two bosses can spam instant death attacks; zombie hydra will frequently dual cast death (which seems to ALWAYS kill on epic difficulty), and the valkyrie has lance who can randomly use the ion cannon to wipe you out (and will rarely succumb to seal despite being vulnerable to it) as well as dual nukes, which is basically game over unless you can dish out insane damage in two turns.
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You might think that the hidras' dual instakill is bad, but at least it doesn't have the turn of dreadful anticipation of valkirie's dual nukes.
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the guardian boss is impossible on epic. It can damage in one round over 10k. Nothing can defend against that.
And if your stuns don't work you're bummed. really crap. Tough and tactics is one thing. outright impossible is another.
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"Many creatures began to mutate from the effects and become vicious, attacking people" yeah like in the first game before the poisonous smoke ^^
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wow i cant believe i beat the tank on my first try looks like all the misfortunate i had in my life just piled up for this big stroke of karma luck
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Let me get this straight... You can get all the way to the end battle on Epic difficulty, just to have the party instant KOed by Ion Cannon?
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The only items needed in this game is Ether, Water of Life, Potion, a few Antidote, a few Mist Potions, and a Few Max Potion. Sell Everything else.
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Guts, I think Impossible Badge is really...Impossible. I've tried a lot of times its even ruining me. Whoever gets it is an R.P.G genius.
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This final boss was easier than the other games... My Strategy: Matt attacks the Tank base, Natz heals an attacks with Pulsar when possible.
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Tip for Minigames: Don't stop attacking. No matter what, keep collecting and obtaining loot. You will easily get enough hearts to keep yourself alive for a good amount of time.
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Why is epic mode so hard. At first it is really easy and then when you get to the Guardian it becomes nearly impossible because the Guardian can kill you in 1 turn
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NoLegs' logic: "Hmm... Should I throw this potion to Matt who has full HP, or to Naz who is dying... Yeah, I guess I'll give it to Matt!"