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Fun, if sometimes frustrating. I have a few suggestions: Make the information you uncover more accessible, like automatically recalling your discoveries about each mix. Include some way to get more coins by potion-making (maybe from the guard), if you really need them. Reduce the number of times you need to click to confirm notifications (have some just disappear or get replaced on their own). Have water quickly available from a bucket or well, since it's used so much.
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It's an interesting game, but it has a few frustrating points. One is that it's incredibly tedious and/or random to get the exact combination you need, once you've narrowed it down. Getting the exact single aspect you need right comes down to luck in getting the appropriate 1/16 chance. Yes, it's not technically random, but the solution is, so in all practicality it's random. For that reason, maybe half the number would be better. I also found that the text often interferred with the actions I was trying to do, which on a few occasions meant botched potions. However, I do like testing various combinations and figure out how everything works.
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first potion i picked said i went back 1 year in time, so i drank it all, i'm 5 years younger, i'm walking away while i'm ahead.