Is there a way for you to include the symbols on all coloured items? This way it enables colourblind people to play without waging a huge guess. I'm had trouble with the chest puzzles, but solved those to watch for 1 white pixel that's on the opposite side for the colours I have trouble with (blue and purple according gf, both blue according me...)
A great addition would be to include a symbol on the enemies that indicates their colour.