I have completed the game two times in game plus mode. ~~~TIPS~~~
1. Only spend your souls on your sword! (TRUST ME)
2. Get the deadly silent skill before fighting the dragon.
3. Don't build a shit ton of shrines. It sucks the challenge out of the game until the 2nd game plus.
4. Money is not an issue. Spend as much as you would like!
5. Army of the Damned>Phoenix>Rampage. This is by damage.
6. You won't complete all of your skills before fighting the final boss for the first time. During the first game plus, you should be able to finish it midway through.
7. I use catapults and the dragon for sieges. (Focus on the castle)
8. Sieges become extremely easy after completing the game and going onto game plus. (Castle HP stays the same while you get stronger.)
9. Dying is not an issue unless you are in the second game plus.
10. You can get rid of the run away skill if you want to make room for another skill.
Here is a tip, pick the highest amount of AUTO G/S ore, leave it over night. Bam, tons of money. If you want gems, put it on one that can insta-mine.(Recommend that you pick the one with the most AUTO G/S) Then leave it over night. :)
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It's Isis, like the Egyptian god. It's not an acronym.