CCleaner and other cleaner utilities like it will empty your flash cache where lots of games store their saves. You can make manual backups of your save by using the save exporter in the More Options screen in the game
Try shift+clicking the portrait to fast buy for now. There's a small overhaul to that screen on the backburner that will eventually make it easier to upgrade quickly but I don't know when we'll get to it yet
ありがとう!