I just beat the game, killed every single survivor. The worst Affinity is "Grim Reaper," you get it after completely killing off all the survivors of 6 or so cities.
Flare maxes out at lvl80 5.55dmg /.5 sec
Saving all survivors is impossible, especially at mumbai. Don't attempt Mumbai until you have a few abilities that can wipe out the entire screen.
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