It's bad that gold heals you a lot more, through buying potions, than the heal dice does. Makes the healing totally useless before you even consider that extra gold is saved after the match, even if you lose the battle. That needs a major rebalance somehow.
1 prestige point per 50 waves is an unreasonably low amount. you are better off prestiging immediately rather than grinding for 50 waves (with all the randomness associated with that) just for one extra point.
I left my game idle overnight, spent massive amounts on upgrades, and my max hasn't gone up in several tries because of how random it is. Obviously something is wrong here. Add defense skills - dodge, regen, armor, etc. Add a secondary gun that is weaker but shoots guys in the air. Add something so the game isn't just a gamble on when you will get shot.
@Detlef, if you went from 163 foam to 0 then yes you would lose your entire 163% bonus. But if you went from 326 to 163 then you only lose 50% of your bonus. Also going from 160% to 257% would increase that bonus by 60% not 97%, since 257 is ~1.6x 160. You need to think about it in terms of relative gains, not absolutes.
Once you prestige a bit it does get more interesting with all the upgrades. Warning for folks: the energy cores cost quantum foam. Probably obvious but I wasn't sure until I clicked it.
Needs more upgrades. Something to make the balls go faster, or get bigger, or a % chance for a critical merge, etc. Your title shows you know there are other games similar to this - go look at what works in those and borrow it.
Until 100B matter (main resource) there are only 3 upgrades, but theres more stuff that unlocks later on like Quantum Foam with respective upgrades, isotopes, molecules and more (so we have about 15 upgrades in the end)
The opening of the game is a total failure. No instructions for what we are supposed to do. I sat there clicking stuff like a dummy for longer than I should have (to be fair, I am dumb). You should either have a tutorial or have a ball already in play.
Something weird happened where I should have died but instead of that my HP just said NaN and I couldn't take damage anymore. Let me kill the titan earlier than I should have.
 "Dice Dynasty"){kind=icon}
 "Infinite Arena"){kind=icon}
 "Yet another Merge Game"){kind=icon}
 "Absorber"){kind=icon}
 "Brick Breaker - Idle Merge"){kind=icon}
Major rebalance done! Heal dice are better than gold/potions now.